Aldehyde dehydrogenase family 1 member L1 (Aldh1L1) is a member of the aldehyde dehydrogenase family. This protein is an enzyme that catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. It is an astrocyte marker and also is expressed in the liver. It is proposed to play a role in regulation of cellular THF levels and inhibiting cell proliferation. Alterations in Aldh1L1 have been implicated in Congenital Hydrocephalus
Protein amino acids 1-902 (full-length) of rat Aldh1L1(also known as 10-formyltetrahydrofolate dehydrogenase, 10-FTHFDH, FBP-CI and Fthfd, accession number P28037); Mouse: 97% identity (875/902 amino acids identical); Human: 91% identity (823/902 amino acids identical); ~70% identity with Aldh1L2
Human, Mouse, Rat
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
No cross-reactivity against Aldh1L2
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from opening
Cytosolic 10-formyltetrahydrofolate dehydrogenase (10-FTHFDH) (FDH) (EC 22.214.171.124) (Aldehyde dehydrogenase family 1 member L1) (FBP-CI)