Anti-Aldh1L1 (Blotting) Antibody (N103/39)
Primary Antibody
Human, Mouse, Non-Human Primate, Rat
N103/39
ICC, IHC, WB
Mouse
Purified
Aldh1l1 Fthfd
100 kDa
Immunohistochemistry (IHC) staining of Rhesus macaque brain for astrocyte marker Aldh1L1 using Anti-Aldh1L1 Antibody 75-140 (clone N103/39, 1:3000). Tissue was perfusion fixed with 4% paraformaldehyde and 0.1% glutaraldehyde, then drop-fixed in 4% paraformaldehyde for 24 h. Sections were cut in 60 μm thick coronal sections using a vibrating microtome. Image courtesy of Adriana Galvan (Emory University). Additional experimental details can be found at: pubmed.ncbi.nlm.nih.gov/35202614.
Product Specific References for Applications and Species
- Immunocytochemistry: Human | Mouse
- Immunohistochemistry: Human | Mouse | Non-Human Primate
- Western Blot: Human | Mouse | Rat
| Immunocytochemistry: Human | ||
| PMID | Dilution | Publication |
| 35276083 | 1:50 | Arredondo, C., et al. 2022. Excessive release of inorganic phosphate by ALS/FTD astrocytes causes non-cell-autonomous toxicity to motoneurons.. Neuron, 1-15. |
| 26295203 | 1:5 (supe) | Zhang, P.W., et al. 2016. Generation of GFAP:: GFP astrocyte reporter lines from human adult fibroblast‐derived i PS cells using zinc‐finger nuclease technology.. Glia, 63-75. |
| 24610630 | 1:25 (supe) | Van Brocklyn, J.R., et al. 2014. Human induced pluripotent stem cells are a novel source of neural progenitor cells (iNPCs) that migrate and integrate in the rodent spinal cord.. Journal of Comparative Neurology, 2707-2728. |
| 23839956 | not listed | McGivern, J.V., et al. 2013. Spinal muscular atrophy astrocytes exhibit abnormal calcium regulation and reduced growth factor production.. Glia, 1418-1428. |
| Immunocytochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 32637606 | not listed | Damisah, E.C., et al. 2020. Astrocytes and microglia play orchestrated roles and respect phagocytic territories during neuronal corpse removal in vivo.. Science advances, eaba3239. |
| 27396343 | 1:200 | Tian, E., et al. 2016. Small-molecule-based lineage reprogramming creates functional astrocytes. . Cell reports, 781-792. |
| 22801498 | 1:10 | Lee, Y., et al. 2012. Oligodendroglia metabolically support axons and contribute to neurodegeneration.. Nature, 443-448. |
| Immunohistochemistry: Human | ||
| PMID | Dilution | Publication |
| 31227709 | 1:500 | Sorrells, S.F., et al. 2019. Immature excitatory neurons develop during adolescence in the human amygdala. . Nature communications, 44576. |
| 30154505 | 1:200 | Kelley, K.W., et al. 2018. Variation among intact tissue samples reveals the core transcriptional features of human CNS cell classes. . Nature neuroscience, 1171-1184. |
| 25622143 | 0.25 | Orr, A.G., et al. 2015. Astrocytic adenosine receptor A 2A and G s-coupled signaling regulate memory. . Nature neuroscience, 423-434. |
| 25209836 | not listed | Surgucheva, I., et al. 2014. New α- and γ-synuclein immunopathological lesions in human brain.. Acta Neuropathol Commun., 1-9. |
| Immunohistochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 34974536 | 1:200 | Bizen, N., et al. 2022. Ddx20, an Olig2 binding factor, governs the survival of neural and oligodendrocyte progenitor cells via proper Mdm2 splicing and p53 suppression. . Cell Death & Differentiation, 1-14. |
| 34582787 | 1:200 | Wang, L.L., et al. 2021. Revisiting astrocyte to neuron conversion with lineage tracing in vivo. . Cell, 5465-5481. |
| 33877363 | 1:500 | Li, A.M., et al. 2021. Intravital Imaging of Neocortical Heterotopia Reveals Aberrant Axonal Pathfinding and Myelination around Ectopic Neurons. . Cerebral Cortex, 4340-4356. |
| 33606320 | 1:2000 | Lowery, R.L., et al. 2021. Microglia and astrocytes show limited, acute alterations in morphology and protein expression following a single developmental alcohol exposure.. Journal of neuroscience Research, 2008-2025. |
| 33441399 | 1:100 | Jain, M., et al. 2021. SRF is required for maintenance of astrocytes in non-reactive state in the mammalian brain.. Eneuro, ENEURO.0447-19.2020. |
| 31587290 | 1:200 | Terumitsu‐Tsujita, M., et al. 2020. Glial pathology in a novel spontaneous mutant mouse of the Eif2b5 gene: a vanishing white matter disease model.. Journal of neurochemistry, 25-40. |
| 31747607 | 1:5 (supe) | Luo, H., et al. 2019. Interleukin-17 regulates neuron-glial communications, synaptic transmission, and neuropathic pain after chemotherapy. . Cell Reports, 2384-2397. |
| 29161339 | 1:50 | Chen, C., et al. 2019. Astrocyte-specific deletion of Sox2 promotes functional recovery after traumatic brain injury. . Cerebral Cortex, 54-69. |
| 29382710 | not listed | Zuo, H., et al. 2018. Age-dependent decline in fate switch from NG2 cells to astrocytes after Olig2 deletion. . Journal of Neuroscience, 2359-2371. |
| 28821665 | 1:5 (supe) | Morel, L., et al. 2017. Molecular and functional properties of regional astrocytes in the adult brain. . Journal of Neuroscience, 8706-8717. |
| 26014473 | 1:250 | Kolson, D.R., et al. 2016. Temporal patterns of gene expression during calyx of held development.. Developmental Neurobiology, 166-189. |
| 26193667 | 1:100 | De Castro, G.M., et al. 2015. Astrocyte activation via Stat3 signaling determines the balance of oligodendrocyte versus Schwann cell remyelination.. The American Journal of Pathology, 2431-2440. |
| 23831026 | 1:3 (supe) | Hu, X., et al. 2013. BACE1 regulates hippocampal astrogenesis via the Jagged1-Notch pathway.. Cell reports, 40-49. |
| 22674276 | 1:100 | Lu, P.P., et al. 2012. A critical cell-intrinsic role for serum response factor in glial specification in the CNS.. Journal of Neuroscience, 8012-8023. |
| 21880926 | 1:100 | De Biase, L.M., et al. 2011. NMDA receptor signaling in oligodendrocyte progenitors is not required for oligodendrogenesis and myelination.. Journal of Neuroscience, 12650-12662. |
| 21092857 | 1:100 | Kang, S.H., et al. 2010. NG2+ CNS glial progenitors remain committed to the oligodendrocyte lineage in postnatal life and following neurodegeneration.. Neuron, 668-681. |
| 19595677 | 1:100 | Lee, J., et al. 2009. Glioma-induced remodeling of the neurovascular unit.. Brain Research, 125-134. |
| Immunohistochemistry: Non-Human Primate | ||
| PMID | Dilution | Publication |
| 35202614 | 2.125 | Heffernan K.S., et al. 2022. Characterization of the GfaABC1D promoter to selectively target astrocytes in the rhesus macaque brain.. Journal of neuroscience methods, 109530. |
| Western Blot: Human | ||
| PMID | Dilution | Publication |
| 29311134 | 1:5 (supe) | Kidana, K., et al. 2018. Loss of kallikrein‐related peptidase 7 exacerbates amyloid pathology in Alzheimer's disease model mice.. EMBO molecular medicine, 8184. |
| 25106428 | 1:500 | Van Brocklyn, J.R., et al. 2014. Aurora-A inhibition offers a novel therapy effective against intracranial glioblastoma.. Cancer Research, 5364-5370. |
| Western Blot: Mouse | ||
| PMID | Dilution | Publication |
| 31515491 | 1:20 (supe) | Men, Y., et al. 2019. Exosome reporter mice reveal the involvement of exosomes in mediating neuron to astroglia communication in the CNS.. Nature communications, 1-18. |
| 25131692 | 1:2000 | Abazyan, S., et al. 2014. Mutant disrupted-in-schizophrenia 1 in astrocytes: focus on glutamate metabolism.. Journal of Neuroscience Research, 1659-1668. |
| 23364798 | not listed | Morel, L., et al. 2013. Neuronal exosomal miRNA-dependent translational regulation of astroglial glutamate transporter GLT1.. Journal of Biological Chemistry, 7105-7116. |
| Western Blot: Rat | ||
| PMID | Dilution | Publication |
| 33090569 | 1:1000 | Tamura, K., et al. 2020. EphA4 regulates Aβ production via BACE1 expression in neurons. . The FASEB Journal, 16383-16396. |
| 27908976 | 1:500 | Wolfes, A.C., et al. 2017. A novel method for culturing stellate astrocytes reveals spatially distinct Ca2+ signaling and vesicle recycling in astrocytic processes.. Journal of General Physiology, 149-170. |
| 23932971 | not listed | Henriquez, B., et al. 2013. Ezh1 and Ezh2 differentially regulate PSD-95 gene transcription in developing hippocampal neurons.. Molecular and Cellular Neuroscience, 130-143. |
| 23555943 | 1:1000 | Souza, D.G., et al. 2013. Characterization of adult rat astrocyte cultures.. PloS one, e60282. |
| 20660562 | not listed | Burzomato, V., et al. 2010. The receptor subunits generating NMDA receptor mediated currents in oligodendrocytes.. The Journal of Physiology, 3403-3414. |