BAFF (B-cell Activation Factor), also known as Tumor Necrosis Factor Superfamily member 13B (TNFSF13B), is expressed in B cell lineage cells and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Mouse BAFF Recombinant Protein is purified b-cell activation factor produced in yeast.
BAFF (B-cell Activation Factor), also known as Tumor Necrosis Factor Superfamily member 13B (TNFSF13B), is a member of the tumor necrosis factor (TNF) ligand family. Nineteen cytokine ligands have been identified as part of the TNF family on the basis of sequence, functional, and structural similarities. Family members include TNF beta (TNFSF1), TNF alpha (TNFSF2), Lymphotoxin beta (TNFSF3), OX40 Ligand (TNFSF4), CD40 Ligand (TNFSF5), Fas Ligand (TNFSF6), CD27 Ligand (TNFSF7), CD30 Ligand (TNFSF8), 4-1BB Ligand (TNFSF9), TRAIL (TNFSF10), TRANCE/RANKL (TNFSF11), TWEAK (TNFSF12), APRIL(TNFSF13), BAFF (TNFSF13B), LIGHT (TNFSF14), TL1A/VEGI (TNFSF15), and GITR Ligand (TNFSF18).
BAFF is expressed in B cell lineage cells and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells.
For research use only. Not for use in diagnostic procedures.
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The Mouse BAFF protein can be used in cell culture, as a BAFF ELISA Standard, and as a Western Blot Control.
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