Anti-Tyrosine Hydroxylase Antibody

Two antipeptide antibodies were generated in chickens against sequences shared between the mouse (P24529) and human (P07101) gene products. Antibodies were affinity-purified and then mixed in equal concentrations. These antibodies have been validated with human, mouse and rat tissues.


Volume: 1000 µL
Sale price$455.00

Product Specific References for Applications and Species

Immunocytochemistry: Mouse
PMID Dilution Publication
287251811:1000Vastagh, C., et al. 2017. Impact of Proestrus on Gene Expression in the Medial Preoptic Area of Mice. Frontiers in Cellular Neuroscience, 183.
Immunocytochemistry: Rat
PMID Dilution Publication
270983761:1000Jaumotte, J.D., et al. 2016. Protection of cultured dopamine neurons from MPP+ requires a combination of neurotrophic factors. European Journal of Neuroscience, 1691-1699.
Immunohistochemistry: Human
PMID Dilution Publication
34856121not listedEicher, A.K., et al. 2021. Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells. Cell stem Cell, 36-51.
Immunohistochemistry: Mouse
PMID Dilution Publication
376574401:2000Rojo, D, et al. 2023. BMAL1 loss in oligodendroglia contributes to abnormal myelination and sleep. Neuron, .
376574411:200Willmore, L, et al. 2023. Overlapping representations of food and social stimuli in mouse VTA dopamine neurons. Neuron, .
374039781:2000Leon-Mercado, L, et al. 2023. Evidence of Extraganglionic Vagal Mechanoreceptors in the Mouse Vagus Nerve. Journal of Anatomy, 0.
373912701:2000Kelly, L, et al. 2023. Subunit-specific Expression and Function of AMPA Receptors in the Mouse Locus Coeruleus. Journal of Anatomy, 0.
368946541:1000Gu, X., et al. 2023. Neurons in the Caudal Ventrolateral Medulla Mediate Descending Pain Control. Nature Neuroscience, 594-605.
368892821:1000Choi, M., et al. 2023. FGF21 Counteracts Alcohol Intoxication by Activating the Noradrenergic Nervous System. Cell Metabolism, 429-437.e5.
368571881:500Ji, Y.W., et al. 2023. Differential Remodeling of Subthalamic Projections to Basal Ganglia Output Nuclei and Locomotor Deficits in 6-OHDA-Induced Hemiparkinsonian Mice. Cell Reports, 112178.
366242761:1000Villadiego, J., et al. 2023. Full protection from SARS-CoV-2 brain infection and damage in susceptible transgenic mice conferred by MVA-CoV2-S vaccine candidate. Nature Neuroscience, 226-238.
365983311:500Fan, J.P., et al. 2023. Subthalamic neurons interact with nigral dopaminergic neurons to regulate movement in mice. Acta Physiologica, e13917.
359774981:1500Ambrosi, P., et al. 2022. Striatonigrostriatal circuit architecture for disinhibition of dopamine signaling. Cell reports, 111228.
357154181:200Liu, Z., et al. 2022. Deficiency in endocannabinoid synthase DAGLB contributes to early onset Parkinsonism and murine nigral dopaminergic neuron dysfunction. Nature communications, 3490.
35650441not listedBreton-Provencher, V., et al. 2022. Spatiotemporal dynamics of noradrenaline during learned behaviour. Nature, 732-738.
356189501:1000Bian, W.J., et al. 2022. Adolescent sleep shapes social novelty preference in mice. Nature neuroscience, 912-923.
351343271:1000Seiler, J.L., et al. 2022. Dopamine signaling in the dorsomedial striatum promotes compulsive behavior. Current Biology, 1175-1188.
35021098not listedScarpa, L.L., et al. 2022. Mice hypomorphic for Pitx3 show robust entrainment of circadian behavioral and metabolic rhythms to scheduled feeding. Cell reports, 109865.
347071061:200Wang, Y., et al. 2021. The essential role of transcription factor Pitx3 in preventing mesodiencephalic dopaminergic neurodegeneration and maintaining neuronal subtype identities during aging. Cell Death & Disease, 1008.
339660441:1000Dinh, E., et al. 2021. TP53INP1 exerts neuroprotection under ageing and Parkinson’s disease-related stress condition. Cell Death & Disease, 460.
334215651:500Liu, J., et al. 2021. Facilitation of GluN2C-containing NMDA receptors in the external globus pallidus increases firing of fast spiking neurons and improves motor function in a hemiparkinsonian mouse model. Neurobiology of Disease, 105254.
32356570not listedBookout, A.L., et al. 2021. Characterization of a cell bridge variant connecting the nodose and superior cervical ganglia in the mouse: prevalence, anatomical features, and practical implications. Journal of Comparative Neurology, 111-128.
333084781:500Kim, C.K., et al. 2020. A molecular calcium integrator reveals a striatal cell type driving aversion. Cell, 2003-2019.
332774921:1000Beas, S.B., et al. 2020. A ventrolateral medulla-midline thalamic circuit for hypoglycemic feeding. Nature Communications, 6218.
332305471:1000Kuerbitz, J., et al. 2020. Temporally Distinct Roles for the Zinc Finger Transcription Factor Sp8 in the Generation and Migration of Dorsal Lateral Ganglionic Eminence (dLGE)-Derived Neuronal Subtypes in the Mouse. Cerebral Cortex, 1744-1762.
326418261:200Muller, P.A., et al. 2020. Microbiota modulate sympathetic neurons via a gut–brain circuit. Nature, 441-446.
31399635not listedUnderhill, S.M., et al. 2019. Amphetamines signal through intracellular TAAR1 receptors coupled to Gα 13 and Gα S in discrete subcellular domains. Molecular Psychiatry, 1208-1223.
313658621:500Wu, J., et al. 2019. Distinct Connectivity and Functionality of Aldehyde Dehydrogenase 1a1-Positive Nigrostriatal Dopaminergic Neurons in Motor Learning. Cell Reports, 1167-1181.
313488901:2000Parker, K.E., et al. 2019. A Paranigral VTA Nociceptin Circuit that Constrains Motivation for Reward.. Cell, 653-671.
312913481:1000Schiffino, F.L., et al. 2019. Activation of a lateral hypothalamic-ventral tegmental circuit gates motivation. PloS One, e0219522.
310369441:1000Vetere, G., et al. 2019. Memory formation in the absence of experience. Nature Neuroscience, 933-940.
307238931:2000Kruse, S.W., et al. 2019. Effect of monoamine reuptake inhibition and α1 blockade on respiratory arrest and death following electroshock‐induced seizures in mice. Epilepsia, 495-507.
306432951:1000Breton-Provencher, V., et al. 2019. Active control of arousal by a locus coeruleus GABAergic circuit. Nature Neuroscience, 218-228.
305920421:1000Angelova, A., et al. 2019. Characterization of perinatally born glutamatergic neurons of the mouse olfactory bulb based on NeuroD6 expression reveals their resistance to sensory deprivation.. Journal of Comparative Neurology, 1245-1260.
30948828not listedSzablowski, J.O., et al. 2018. Acoustically targeted chemogenetics for the non-invasive control of neural circuits. Nature Biomedical Engineering, 475-484.
305243761:1000Bardóczi, S., et al. 2018. GnRH Neurons Provide Direct Input to Hypothalamic Tyrosine Hydroxylase Immunoreactive Neurons Which Is Maintained During Lactation. Frontiers in Endocrinology, 685.
304783401:100Colina, C., et al. 2018. Selective tracking of FFAR3-expressing neurons supports receptor coupling to N-type calcium channels in mouse sympathetic neurons. Scientfic Reports, 17379.
303931441:200-1:250Gil-Tommee, C., et al. 2018. Parkinsonian GM2 synthase mice lacking mature gangliosides develop urinary dysfunction and neurogenic bladder. Experimental Neurology, 265-273.
296913291:1500Barry, J., et al. 2018. Striatal Direct and Indirect Pathway Output Structures are Differentially Altered in Mouse Models of Huntington's Disease. The Journal of Neuroscience, 4678-4694.
290562971:1000Nishiyama, J., et al. 2017. Virus-Mediated Genome Editing via Homology- Directed Repair in Mitotic and Postmitotic Cells in Mammalian Brain. Neuron, 755-768.
290353641:1000Pirzgalska, R.N., et al. 2017. Sympathetic neuron–associated macrophages contribute to obesity by importing and metabolizing norepinephrine. Nature Medicine, 1309-1318.
289721221:1000Tiveron, M.C., et al. 2017. Zic-Proteins Are Repressors of Dopaminergic Forebrain Fate in Mice and C. elegans. The Journal of Neuroscience, 10611-10623.
288143421:500Qin, S., et al. 2017. Septal contributions to olfactory bulb interneuron diversity in the embryonic mouse telencephalon: role of the homeobox gene Gsx2. Neural Development, 13.
287080611:2000McCall, J.G., et al. 2017. Locus coeruleus to basolateral amygdala noradrenergic projections promote anxiety-like behavior. eLife, e18247.
286899841:500De Biase, L.M., et al. 2017. Local cues establish and maintain region-specific phenotypes of basal ganglia microglia. Neuron, 341-356.
286026901:500Cho, R.C., et al. 2017. Dorsal Raphe Dopamine Neurons Modulate Arousal and Promote Wakefulness by Salient Stimuli. Neuron, 1205-1219.
284728581:1000Merchan-Sala, P., et al. 2017. Selective neuronal expression of the SoxE factor, Sox8, in direct pathway striatal projection neurons of the developing mouse brain. The Journal of Comparative Neurology Research in Systems Neuroscience, 2805-2819.
283679721:1000Pereira, M., et al. 2017. A brain-sparing diphtheria toxin for chemical genetic ablation of peripheral cell lineages. Nature Communications, 14967.
282835581:1000Pomeranz, L.E., et al. 2017. Gene Expression Profiling with Cre-Conditional Pseudorabies Virus Reveals a Subset of Midbrain Neurons That Participate in Reward Circuitry. The Journal of Neuroscience, 4128-4144.
281328301:1000Shin, G., et al. 2017. Flexible Near-Field Wireless Optoelectronics as Subdermal Implants for Broad Applications in Optogenetics. Neuron, 509-521.
268783811:500Kim, C.K., et al. 2016. Simultaneous fast measurement of circuit dynamics at multiple sites across the mammalian brain. Nature Methods, 325-328.
254032541:1000Muzerelle, A., et al. 2016. Conditional anterograde tracing reveals distinct targeting of individual serotonin cell groups (B5–B9) to the forebrain and brainstem. Brain Structure and Function, 535-561.
249279311:1000Vasistha, N.A., et al. 2015. Cortical and clonal contribution of Tbr2 expressing progenitors in the developing mouse brain. Cerebral Cortex, 3290-3302.
237878191:2000Al-Hasani, R., et al. 2013. Locus coeruleus kappa-opioid receptors modulate reinstatement of cocaine place preference through a noradrenergic mechanism. Neuropsychopharmacology, 2484-2497.
218588211:1000Erickson, C.S., et al. 2012. Sacral neural crest-derived cells enter the aganglionic colon of Ednrb-/- mice along extrinsic nerve fibers.. Journal of Comparative Neurology, 620-632.
348243971:2000Qazi, R., et al. 2009. Scalable and modular wireless-network infrastructure for large-scale behavioural neuroscience. Nature biomedical engineering, 771-786.
Immunohistochemistry: Rat
PMID Dilution Publication
367645771:1000Lepreux, G., et al. 2023. Recapitulating Phenotypes of Alcohol Dependence via Overexpression of Oprk1 in the Ventral Tegmental Area of Non-Dependent TH::Cre Rats. Neuropharmacology, 109457.
351343251:200van Elzelingen, W., et al. 2022. Striatal dopamine signals are region specific and temporally stable across action-sequence habit formation. Current Biology, 1163-1174.
333267751:500-1:1000Choi, J.Y., et al. 2020. A comparison of dopaminergic and cholinergic populations reveals unique contributions of VTA dopamine neurons to short-term memory. Cell Reports, 108492.
307284471:2000Johnson, A.R., et al. 2019. Cues play a critical role in estrous cycle-dependent enhancement of cocaine reinforcement. Neuropsychopharmacology, 1189-1197.
298599721:1000Glennon, E., et al. 2019. Locus coeruleus activation accelerates perceptual learning. Brain Research, 39-49.
218588191:500Tan, W., et al. 2012. Reelin demarcates a subset of pre-Bötzinger complex neurons in adult rat.. Journal of Comparative Neurology, 606-619.
Additional Publications: Unspecified
PMID Publication
32599671Boccalaro, I.L., et al. 2020. Dopamine depletion induces neuron‐specific alterations of GABAergic transmission in the mouse striatum. European Journal of Neuroscience, 3353-3374.
25782435Thibault, D., et al. 2016. Homeostatic regulation of excitatory synapses on striatal medium spiny neurons expressing the D2 dopamine receptor. Brain Structure and Function, 2093-2107.
25216299Bonzano, S., et al. 2014. Odour enrichment increases adult‐born dopaminergic neurons in the mouse olfactory bulb. European Journal of Neuroscience, 3450-3457.
24916473Jaumotte, J.D., et al. 2014. Comparison of GDF5 and GDNF as neuroprotective factors for postnatal dopamine neurons in ventral mesencephalic cultures. Journal of Neuroscience Research, 1425-1433.
21326331Van der Perren, A., et al. 2011. Efficient and stable transduction of dopaminergic neurons in rat substantia nigra by rAAV 2/1, 2/2, 2/5, 2/6.2, 2/7, 2/8 and 2/9. Gene Therapy, 517-527.

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