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In March, researchers around the world cited ImmunoChemistry Technologies’ products in their publications. Explore our selection of March citations from 2019.

Polishchuk EV, Merolla A, Lichtmannegger J, Romano A, Indrieri A, Ilyechova EY, Concilli M, De Cegli R, Crispino R, Mariniello M, Petruzzelli R, Ranucci G, Iorio R, Pietrocola F, Einer C, Borchard S, Zibert A, Schmidt HH, Di Schiavi E, Puchkova LV, Franco B, Kroemer G, Zischka H, Polishchuk RS. Activation of Autophagy, Observed in Liver Tissues From Patients With Wilson Disease and From ATP7B-Deficient Animals, Protects Hepatocytes From Copper-Induced Apoptosis. Gastroenterology. 2019 Mar;156(4):1173-1189.e5. doi: 10.1053/j.gastro.2018.11.032. Epub 2018 Nov 17. Abstract

"To evaluate lysosomal acidification or proteolytic activity, the cells were loaded with LysoTracker Red (Life Technologies, Carlsbad, CA) or with DQ self-quenched bovine serum albumin (DQ-BSA; ThermoFisher Scientific, Waltham, MA) and Magic Red (ImmunoChemistry Technologies, Bloomington, MN), respectively, according to the manufacturer’s instructions."

Kaasinen E, Kuismin O, Rajamäki K, Ristolainen H, Aavikko M, Kondelin J, Saarinen S, Berta DG, Katainen R, Hirvonen EAM, Karhu A, Taira A, Tanskanen T, Alkodsi A, Taipale M, Morgunova E, Franssila K, Lehtonen R, Mäkinen M, Aittomäki K, Palotie A, Kurki MI, Pietiläinen O, Hilpert M, Saarentaus E, Niinimäki J, Junttila J, Kaikkonen K, Vahteristo P, Skoda RC, Seppänen MRJ, Eklund KK, Taipale J, Kilpivaara O, Aaltonen LA. Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humans. Nat Commun 2019 Mar 19;10(1):1252. doi: 10.1038/s41467-019-09198-7. Full Text

"FAM-FLICA Caspase-1 Detection Kit (ImmunoChemistry Technologies, LLC., Bloomington, MN, USA) was then used according to the manufacturer protocol."

Kang YH, Biswas A, Field M, Snapper SB. STAT1 signaling shields T cells from NK cell-mediated cytotoxicity. Nat Commun. 2019 Feb 22;10(1):912. doi: 10.1038/s41467-019-08743-8. Full Text

"For assessment of cell death, cells were stained with the FAM-FLICA Poly Caspase Kit (ImmunoChemistry Technologies) for 1 h at 37 °C in T-cell media prior to antibody surface staining."

Wilhelm I, Levit-Zerdoun E, Jakob J, Villringer S, Frensch M, Übelhart R, Landi A, Müller P, Imberty A, Thuenauer R, Claudinon J, Jumaa H, Reth M, Eibel H, Hobeika E, Römer W. Carbohydrate-dependent B cell activation by fucose-binding bacterial lectins. Sci Signal. 2019 Mar 5;12(571). pii: eaao7194. doi: 10.1126/scisignal.aao7194. Abstract

"Cells were stained with the SR-FLICA Caspase Assay Kit (ImmunoChemistry Technologies) according to the manufacturer’s instructions." Aljabri A, Vijayan V, Stankov M, Nikolin C, Figueiredo C, Blasczyk R, Becker JU, Linkermann A, Immenschuh S. HLA class II antibodies induce necrotic cell death in human endothelial cells via a lysosomal membrane permeabilization-mediated pathway. Cell Death Dis. 2019 Mar 8;10(3):235. doi: 10.1038/s41419-019-1319-5. Full Text

"Magic red cathepsin B and L assay kits and AO were from ImmunoChemistry Technologies (Bloomington, MN, USA)."

Maimouni S, Lee MH, Sung YM, Hall M, Roy A, Ouaari C, Hwang YS, Spivak J, Glasgow E, Swift M, Patel J, Cheema A, Kumar D, Byers S. Tumor suppressor RARRES1 links tubulin deglutamylation to mitochondrial metabolism and cell survival. Oncotarget 2019 Feb 26;10(17):1606-1624. doi: 10.18632/oncotarget.26600. eCollection 2019 Feb 26. Full Text

"...Tetramethylrhodamine methylester (TMRM), a lipophilic cationic fluorescent redistribution dye was applied to detect the mitochondrial membrane potential (D) from MitoPT TMRE & TMRM Assay Kits (ImmunoChemistry Technologies). Cells in complete growth medium were loaded for 20 min at 37°C with 70 nM of TMRM and shaken."

Products Used:
FAM-FLICA Caspase-1 Assay
FAM-FLICA Poly Caspase Assay
SR-FLICA Poly Caspase Assay
Magic Red Cathepsin B Assay
Magic Red Cathepsin L Assay
MitoPT TMRM Assay