The Kv channel-interacting proteins (KChIP1, kChIp2, kChIp3, and kChIp4) are members of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin or neuronal calcium sensor (NCS) family branch of the EF-hand superfamily. They serve as auxiliary channel subunits and interact with Kv4 alpha subunits to form native Kv4 channel complexes. KChiP subunits regulate Kv4 channels through various mechanisms including altering: channel density, inactivation kinetics, rate of recovery from inactivation, and cell surface delivery.
IHC, IP, WB
33 kDa (KChIP2)25 kDa (KChIP3/4)22 kDa (KChIP1)
Fusion protein amino acids 1-216 (full length) of rat KChIP1b (accession number Q8R426); Human: 99.5% identity (215/216 amino acids); Mouse=100% identity (216/216 amino acids)
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
No cross-reactivity reported
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from opening
Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel modulatory protein 1) (Potassium channel-interacting protein 1)
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