Anti-Pan-KChIP K+ Channel Antibody (K55/82)
Our Anti-Pan-KChIP K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K55/82. It detects human, mouse, and rat Pan-KChIP K+ channel, and is purified by Protein A chromatography. It is great for use in CHiP, IHC, ICC, IP, WB.
![Immunoblot versus crude brain membranes from adult mouse (MBM), rat (RBM) and human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] and cerebellum [HBM(Cb)] probed with K55/82 (left) and N52A/42 (right) TC supe.](http://www.antibodiesinc.com/cdn/shop/products/validation-image-73-006-k55-82-wb-2_{width}x.jpg?v=1626902803)
Adult rat hippocampus immunohistochemistry.
![Immunoblot versus crude brain membranes from adult mouse (MBM), rat (RBM) and human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] and cerebellum [HBM(Cb)] probed with K55/82 (left) and N52A/42 (right) TC supe.](http://www.antibodiesinc.com/cdn/shop/products/validation-image-73-006-k55-82-wb-2_1024x.jpg?v=1626902803)
Product Specific References for Applications and Species
- ChIP: Mouse
- Immunocytochemistry: Rat
- Immunohistochemistry: Mouse
- Immunoprecipitation: Mouse
- Patch Clamp Recording: Mouse | Rat
- Western Blot: Human | Mouse | Rat
| Chromatin Immunoprecipitation: Mouse | ||
| PMID | Dilution | Publication |
| 31017573 | 1:50 | Carrillo-Reid, L., et al. 2019. Mutant huntingtin enhances activation of dendritic Kv4 K+ channels in striatal spiny projection neurons.. Elife, e40818. |
| Immunocytochemistry: Rat | ||
| PMID | Dilution | Publication |
| 20154682 | 1:250 | Anderson, D., et al. 2010. Regulation of neuronal activity by Cav3-Kv4 channel signaling complexes.. Nature Neuroscience, 333-7. |
| Immunohistochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 17122038 | not listed | Menegola, M. , et al. 2006. Unanticipated region- and cell-specific downregulation of individual KChIP auxiliary subunit isotypes in Kv4.2 knock-out mouse brain.. Journal of Neuroscience, 2137-42. |
| Immunoprecipitation: Mouse | ||
| PMID | Dilution | Publication |
| 31017573 | 5 ug | Carrillo-Reid, L., et al. 2019. Mutant huntingtin enhances activation of dendritic Kv4 K+ channels in striatal spiny projection neurons.. Elife, e40818. |
| Patch Clamp Recording: Mouse | ||
| PMID | Dilution | Publication |
| 24462100 | not listed | Wang, K., et al. 2014. Distinct Ca2+ sources in dendritic spines of hippocampal CA1 neurons couple to SK and Kv4 channels.. Neuron, 379-387. |
| Patch Clamp Recording: Rat | ||
| PMID | Dilution | Publication |
| 27807163 | 1:100 | Rizwan, A.P., et al. 2016. Long-Term potentiation at the mossy fiber–granule cell relay invokes postsynaptic second-messenger regulation of Kv4 channels.. Journal of Neuroscience, 36(44), pp., 11196-11207. |
| 24966380 | 1:100 | Heath, N.C., et al. 2014. The expression pattern of a Cav3-Kv4 complex differentially regulates spike output in cerebellar granule cells.. Journal of Neuroscience, 8800-8812. |
| Western Blot: Human | ||
| PMID | Dilution | Publication |
| 25032865 | not listed | Carlessi, L., et al. 2014. Functional and molecular defects of hiPSC-derived neurons from patients with ATM deficiency.. Cell Death Disease, e1342-e1342. |
| Western Blot: Mouse | ||
| PMID | Dilution | Publication |
| 31212013 | 1:1000 | Tabor, G.T., et al. 2019. A novel bungarotoxin binding site-tagged construct reveals MAPK-dependent Kv4. 2 trafficking.. Molecular and Cellular Neuroscience, 121-130. |
| 31017573 | 1:1000 | Carrillo-Reid, L., et al. 2019. Mutant huntingtin enhances activation of dendritic Kv4 K+ channels in striatal spiny projection neurons.. Elife, e40818. |
| 21943606 | 1:1000 | Sun, W., et al. 2011. DPP6 establishes the A-type K(+) current gradient critical for the regulation of dendritic excitability in CA1 hippocampal neurons.. Neuron, 1102-15. |
| 19744491 | not listed | Tozakidou, M., et al. 2010. Molecular and functional remodeling of I(to) by angiotensin II in the mouse left ventricle.. Journal of Molecular and Cellular Cardiology, 140-151. |
| 18458082 | not listed | Schwenk, J., et al. 2008. NMR analysis of KChIP4a reveals structural basis for control of surface expression of Kv4 channel complexes.. The Journal of Biological Chemistry, 18937-18946. |
| Western Blot: Rat | ||
| PMID | Dilution | Publication |
| 24109433 | not listed | Verpelli, C., et al. 2013. Comparative neuronal differentiation of self-renewing neural progenitor cell lines obtained from human induced pluripotent stem cells.. Frontiers in Cellular Neuroscience, 175. |
| 22612322 | 1:2000 | Pruunsild, P., et al. 2012. Subcellular localization and transcription regulatory potency of KCNIP/Calsenilin/DREAM/KChIP proteins in cultured primary cortical neurons do not provide support for their role in CRE-dependent gene expression.. Journal of Neurochemistry, 29-43. |
| 18957440 | 1:1000 | Jerng, H.H. , et al. 2008. Multiple Kv channel-interacting proteins contain an N-terminal transmembrane domain that regulates Kv4 channel trafficking and gating.. The Journal of Biological Chemistry, 36046-36059. |