The Kv channel-interacting proteins (KChIP1, kChIp2, kChIp3, and kChIp4) are members of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin or neuronal calcium sensor (NCS) family branch of the EF-hand superfamily. They serve as auxiliary channel subunits and interact with Kv4 alpha subunits to form native Kv4 channel complexes. KChiP subunits regulate Kv4 channels through various mechanisms including altering: channel density, inactivation kinetics, rate of recovery from inactivation, and cell surface delivery.
IHC, IP, WB
33 kDa (KChIP2)25 kDa (KChIP3/4)22 kDa (KChIP1)
Fusion protein amino acids 1-216 (full length) of rat KChIP1b (accession number Q8R426); Human: 99.5% identity (215/216 amino acids); Mouse=100% identity (216/216 amino acids)
Human, Mouse, Rat
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
No cross-reactivity reported
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from opening
Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel modulatory protein 1) (Potassium channel-interacting protein 1)
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