ICC IHC WB
Transient receptor potential cation channel subfamily V (vanilloid) member 1, or TrpV1 is a member of transient receptor potential cation channel family(TRP channel).TrpV1 is a non-selective, ligand activated calcium permeant cation channel that is widely expressed in tissues but elevated in dorsal root ganglia, highly but not solely expressed in postsynaptic dendritic spines. TrpV1 is involved in heat and chemical detection and in pain perception.
Fusion protein amino acids 1-160 (cytoplasmic N-terminus) of rat TrpV1 (also known as Transient receptor potential cation channel subfamily V member 1, Osm-9-like TRP channel 1, OTRPC1, Capsaicin receptor, Vanilloid receptor 1, VR1, Vanilloid receptor type 1-like and Vr1l, accession number O35433)
Mouse: 85% identity (137/161 amino acids identical)
Human: 68% identity (110/161 amino acids identical) <50% identity with TrpV4
Transient receptor potential cation channel subfamily V member 1 (TrpV1) (Capsaicin receptor) (Osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Vanilloid receptor type 1-like)
Trpv1 Vr1 Vr1l
TC Supernatant: AB_10673516
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody has been knockout-validated in mouse brain (by Western blot and/or immunohistochemistry).
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.