Products: Primary Antibodies

Anti-Neurexin-1-Beta (blotting) Antibody (N170A/26)

NeuroMab Logo from NeuroMab

 Datasheet

PRODUCT OPTIONS

Brand Catalog # Option Volume Concentration Price
Brand
NeuroMab Logo
Catalog #
73-217
Option
TC Supernatant
Volume
5 mL
Concentration
Lot dependent
Price
$275.00

Validation Images


Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG1

Species Reactivity:

Human Mouse Rat

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

ICC WB

Target Description:

Neurexin-1Beta is a member of the neurexin family. Neurexin-1Beta is a membrane bound receptor and binds neuroligins and forms complexes at neuronal synapses in the central nervous system. Binding parterns for Neurexin 1beta include CASK, Neuroligins 1-3 and DAG1. Neurexin-1Beta serves as a presynaptic marker and plays an important role in assembling presynaptic and postsynaptic machinery. This protein may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins and possibly plays a role in synaptic junctions formation or maintenance.

Immunogen:

Synthetic peptide amino acids 47-64 (ASSLGAHHIHHFHGSSKH, extracellular N-terminus) of rat Neurexin-1-Beta (accession number Q63373) Human: 100% identity (18/18 amino acids identical)
>60% identity with Neurexin-2-Beta

Cross Reactivity:

Does not cross-react with Neurexin-2-Beta

Protein Name(s):

Neurexin-1-beta (Neurexin I-beta)

Gene Name(s):

NRXN1

Antibody Registry ID:

TC Supernatant: AB_10674585


Antibody Validation and Application Notes


This antibody has been validated using the following assays:
Western Blot:

This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.

Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Molecular Weight:

50 kDa


Quality Control


The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.


Citations and References