Products: Primary Antibodies
PRODUCT OPTIONS
| Catalog # | Option | Volume | Concentration | Price* | |
|---|---|---|---|---|---|
| Catalog # MBP |
Volume Regular vials contain 1000 µL of this antibody mixture; Sampler vials contain 200 µL of this mixture. |
Concentration 100 µg/ml |
Price $399.00 |
Validation Images
Overview
Aves Labs
Polyclonal
Chicken
Human Mouse Rat
ICC IHC WB
Chickens were immunized with a synthetic peptide / keyhole limpet hemocyanin (KLH) conjugate. The peptide corresponded to a region of the MBP gene product shared between the human (NP_002376, NCBI) and mouse (NP_034907, NCBI) sequences. After repeated injections, immune eggs were collected, the IgY fractions were purified from the yolks, and then affinity-purified using a peptide column. The concentrations of the eluates were then adjusted to 100 ug/ml, and the preparation was filter-sterilized.
Myelin basic protein (MBP) (Myelin A1 protein) (Myelin membrane encephalitogenic protein)
MBP
Default Title: AB_2313550
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
Can recognize multiple bands between 14-22 kDa, corresponding to different MBP isoforms
1:1000-1:2000
1:1000-1:2000
Quality Control
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Quality assurance analysis was performed using immunohistochemistry (at a dilution of 1:2000) using fluorescein-labeled goat anti-chicken IgY (1:500 dilution, Aves Labs Cat.# F-1005) as the secondary reagent.
Citations and References
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- Assinck P, Duncan GJ, Plemel JR, Lee MJ, Stratton JA, Manesh SB, Liu J, Ramer LM, Kang SH, Bergles DE, Biernaskie J, Tetzlaff W (2017), 'Myelinogenic Plasticity of Oligodendrocyte Precursor Cells following Spinal Cord Contusion Injury.' The Journal of Neuroscience. 10.1523/JNEUROSCI.2409-16.2017.
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- Tania M. Fowke, Robert Galinsky, Joanne O. Davidson, Guido Wassink, Rashika N. Karunasinghe, Jaya D. Prasad, Laura Bennet, Alistair J. Gunn, Justin M. Dean (2018), 'Loss of interneurons and disruption of perineuronal nets in the cerebral cortex following hypoxia-ischaemia in near-term fetal sheep.' Nature Scientific Reports. 10.1038/s41598-018-36083-y.
- Xu, Zhizhonga,c,; Adilijiang, Abulimitia,c,; Wang, Wenqianga; You, Pana; Lin, Duoduoa; Li, Xinmina,c; He, Jue (2019), 'Arecoline attenuates memory impairment and demyelination in a cuprizone-induced mouse model of schizophrenia.' NeuroReport. 10.1097/WNR.0000000000001172.
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