Anti-c-FOS Antibody (N486/76)

Name: Anti-c-FOS Antibody
Brand: NeuroMab
SKU: 75-511
Price: 319.0 USD
Availability: InStock

Our Anti-c-FOS mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N486/76. It detects human, mouse, and rat c-FOS, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Anti-c-FOS Antibody

Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC, WB

Host Species

Mouse

Available Conjugates

490

550

594

650

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Data Sheet

SKU: 75-511

Volume: 100 µL

Variant

Price:

$319.00

Quantity:

Product Details

Target

c-FOS

Target Description

C-fos belongs the Fos family. Other members include FosB, Fra-1, Fra-2. c-fos binds to JUN/AP1 transcription factor. C-Fos is expressed in placental tissue, fetal liver, developing bone, developing central nervous system, and adult bone marrow. It is expressed in the nucleus and in the endoplasmic reticulum. c-Fos is has a role in signal transduction, cell proliferation, differentiation, and apoptosis. C-Fos is overexpressed in many cancers.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N486/76

Isotype

IgG1

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

FOS, G0S7

Molecular Weight

70 kDa

Antigen

Fusion protein amino acids 1-377 (full-length) of human FOS (accession number P01100) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2927660

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when tested by Western Blot.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Proto-oncogene c-Fos, Cellular oncogene fos, G0/G1 switch regulatory protein 7

UniProt Details

UniProt (Human): P01100
UniProt (Immunogen Species): P01100

Product Specific References for Applications and Species

Immunohistochemistry: Mouse

Immunocytochemistry: Mouse
PMID	Dilution	Publication
34750263	1:5 (supe)	Vierra, N.C., et al. 2021. Regulation of neuronal excitation-transcription coupling by Kv2.1-induced clustering of somatic L-type Ca2+ channels at ER-PM junctions. PNAS: USA, .

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Anti-c-FOS Antibody (N486/76)

SKU: 75-511

Product Details

Product Specific References for Applications and Species

Bulk Order Anti-c-FOS Antibody

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