Products: Primary Antibodies

Anti-CNPase (cyclic nucleotide phosphodiesterase)

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PRODUCT OPTIONS

Catalog #	Option	Volume	Concentration	Price*
Catalog # CNP		Volume Regular vials contain 1000 µL of this antibody mixture; Sampler vials contain 200 µL of this mixture.	Concentration 100 µg/ml	Price $399.00

Validation Images

Overview

Brand:

Aves Labs

Antibody Type:

Polyclonal

Host Species:

Chicken

Species Reactivity:

Human Mouse Rat

Applications:

ICC IHC WB

Immunogen:

Chickens were immunized with a synthetic peptide / keyhole limpet hemocyanin (KLH) conjugate. The peptide corresponded to a region of the CNPase gene product shared between the human (NP_149124, NCBI) and mouse (P16330, NCBI) sequences. After repeated injections, immune eggs were collected, the IgY fractions were purified from the yolks, and then affinity-purified using a peptide column. The concentrations of the eluates were then adjusted to 100 ug/ml, and the preparation was filter-sterilized.

Protein Name(s):

2',3'-cyclic-nucleotide 3'-phosphodiesterase, CNP, CNPase, EC 3.1.4.37

Gene Name(s):

CNP

Antibody Registry ID:

Default Title: AB_2313538

Antibody Validation and Application Notes

This antibody has been validated using the following assays:

Expected Banding Pattern:

47 kDa

Western Dilution Range:

1:500-1:1000

IHC Dilution Range:

1:500-1:1000

Quality Control

The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Quality assurance analysis was performed using immunohistochemistry (at a dilution of 1:2000) using fluorescein-labeled goat anti-chicken IgY (1:500 dilution, Aves Labs Cat.# F-1005) as the secondary reagent.

Citations and References

Beirowski B, Wong KM, Babetto E, Milbrandt J. (2017), 'mTORC1 promotes proliferation of immature Schwann cells and myelin growth of differentiated Schwann cells .' PNAS. 10.1073/pnas.1620761114.
Lin JP, Mironova YA, Shrager P, Giger RJ. (2017), 'LRP1 regulates peroxisome biogenesis and cholesterol homeostasis in oligodendrocytes and is required for proper CNS myelin development and repair.' eLife. 10.7554/eLife.30498.001.