Human Mouse Rat
ICC IHC WB
Fusion protein amino acids 13-297 (N-terminal protein kinase domain) of human Cdkl5 (also known as Cyclin-dependent kinase-like 5, Serine/threonine-protein kinase 9 and STK9, accession number O76039)
Rat: 100% identity (285/285 amino acids identical)
Mouse: 100% identity (285/285 amino acids identical)
50% identity with Cdkl2 and other Cdkl proteins Hybridoma kindly donated by Cornelius Gross, Mouse Biology Unit, EMBL.
Cyclin-dependent kinase-like 5 (EC 184.108.40.206) (Serine/threonine-protein kinase 9)
TC Supernatant: AB_2493091
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody has been knockout-validated in mouse brain (by Western blot and/or immunohistochemistry).
This antibody recognizes a single immunoreactive band of expected molecularweight when used to probe brain lysate.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
Citations and References
- Enga RM1, Rice AC2, Weller P3, Subler MA3, Lee D4, Hall CP4, Windle JJ3, Beardsley PM5, van den Oord EJ6, McClay JL7. (2017), 'Initial characterization of behavior and ketamine response in a mouse knockout of the post-synaptic effector gene Anks1b..' Neurosci Lett. 10.1016/j.neulet.2017.01.044..
- Amendola E1, Zhan Y1, Mattucci C1, Castroflorio E2, Calcagno E2, Fuchs C3, Lonetti G4, Silingardi D5, Vyssotski AL6, Farley D1, Ciani E3, Pizzorusso T4, Giustetto M2, Gross CT1.. (2014), 'Mapping pathological phenotypes in a mouse model of CDKL5 disorder..' PLoS One. 10.1371/journal.pone.0091613.