Products: Primary Antibodies

Anti-Tyrosine Hydroxylase (Ser40) Antibody

PhosphoSolutions Logo from PhosphoSolutions

 Datasheet

Product Summary:

We manufacture our Tyrosine Hydroxylase Ser40 rabbit polyclonal antibody, affinity purified from pooled serum. Great in WB, IHC, and ICC.

PRODUCT OPTIONS

★ Trial Size Available ★
Brand Catalog # Option Volume Concentration Price
Brand
PhosphoSolutions Logo
Catalog #
p1580-40
Option
Standard
Volume
100 µL
Concentration
Lot dependent
Price
$380.00
Brand
PhosphoSolutions Logo
Catalog #
p1580-40-025
Option
Trial Size
Volume
25 µL
Concentration
Lot dependent
Price
$119.00

Validation Images


Product Details

Antibody Type:

Polyclonal

Host Species:

Rabbit

Form:

Antigen Affinity Purified from Pooled Serum

Species Reactivity:

Human Mouse Rabbit Rat

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

ICC IHC WB

Target Description:

Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines Dopamine and Norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling (Witkovsky et al., 2000; Salvatore et al., 2001; Dunkley et al., 2004). The activity of TH is also regulated by phosphorylation (Haycock et al., 1982; Haycock et al., 1992; Jedynak et al., 2002). Phospho-specific antibodies for the phosphorylation sites on TH can be used to great effect in studying this regulation and in identifying the cells in which TH phosphorylation occurs.

Immunogen:

Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser40 conjugated to KLH

Protein Name(s):

Tyrosine Hydroxylase (Ser40), anti tyrosine hydroxylase ser40, anti TH ser40, ser40, anti tyrosine hydroxylase, anti-tyrosine hydroxylase, ptyrosine, phospho th, anti-th, hydoxylase

Gene Name(s):

TH

Antibody Registry ID:

Standard: AB_2492279
Trial Size: AB_2492279


Antibody Validation and Application Notes

Molecular Weight:

60 kDa