Anti-Tyrosine Hydroxylase (Ser40) Antibody

Polyclonal

Rabbit

Antigen Affinity Purified from Pooled Serum

Human Mouse Rabbit Rat

ICC IHC WB

Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines Dopamine and Norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling (Witkovsky et al., 2000; Salvatore et al., 2001; Dunkley et al., 2004). The activity of TH is also regulated by phosphorylation (Haycock et al., 1982; Haycock et al., 1992; Jedynak et al., 2002). Phospho-specific antibodies for the phosphorylation sites on TH can be used to great effect in studying this regulation and in identifying the cells in which TH phosphorylation occurs.

Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser40 conjugated to KLH

Tyrosine Hydroxylase (Ser40), anti tyrosine hydroxylase ser40, anti TH ser40, ser40, anti tyrosine hydroxylase, anti-tyrosine hydroxylase, ptyrosine, phospho th, anti-th, hydoxylase

Standard: AB_2492279
Trial Size: AB_2492279

60 kDa