Immunoblot against extracts of COS cells transiently transfected with Myc/Flag-tagged TWIK-2 or untagged Kv2.1 plasmid probed with N469/28 (left) or rabbit anti-Flag (right)..
TWIK-2 (Potassium channel subfamily K member 6) (Inward rectifying potassium channel protein
TWIK-2) (TWIK-originated similarity sequence) (TWIK-2 two-pore-domain K+ channel)
Potassium two pore domain channel subfamily K member 6 is encoded by the gene KCNK6. KCNK6 is a member of the two pore domain potassium channel (TC 1.A.1.8) family. KCNK6 is considered an open rectifier, and is stimulated by arachidonic acid and inhibited by internal acidification and volatile anaesthetics. KCNK6 is expressed in platelets and testis. Diseases associated with KCNK6 include Thoracic Outlet Syndrome and Gingival Recession.
Fusion protein amino acids 28-92 (first extracellular loop) of mouse TWIK-2 (also known as Potassium channel subfamily K member 6, Inward rectifying potassium channel protein TWIK-2, TWIK-originated similarity sequence, TWIK-2 two-pore-domain K+ channel, Kcnk6, TOSS, MCG22939, RCG53580 isoform CRA_c, LOC100909725 and rCG_53580, accession number Q3TBV4)
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.