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Products: Primary Antibodies

Anti-TFAM (Transcription Factor A, motochondrial) Antibody

PhosphoSolutions Logo from PhosphoSolutions

 Datasheet

Product Summary:

Excellent mitochondrial labeling! Our TFAM rabbit polyclonal antibody is formulated as neat serum. It is excellent for use in WB.

PRODUCT OPTIONS

★ Trial Size Available ★
Brand Catalog # Option Volume Concentration Price
Brand
PhosphoSolutions Logo
Catalog #
2001-TFAM
Option
Standard
Volume
100 µL
Concentration
Lot dependent
Price
$325.00
Brand
PhosphoSolutions Logo
Catalog #
2001-TFAM-025
Option
Trial Size
Volume
25 µL
Concentration
Lot dependent
Price
$119.00

Validation Images


Product Details

Antibody Type:

Polyclonal

Host Species:

Rabbit

Form:

Neat Serum

Species Reactivity:

Human Mouse Rat

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

WB

Target Description:

Mitochondrial Transcription Factor A (TFAM) is a key activator of mitochondrial (mt) DNA transcription as well as a participant in mitochondrial genome replication. mtDNA is highly susceptible to oxidative stress leading to mitochondrial dysfunction. Overexpression of TFAM has been implicated in the amelioration of age dependent impairment of brain functions through the prevention of oxidative stress and mitochondrial dysfunction in microglia (Hayashi et al., 2008). More recently, TFAM overexpression has been shown to potentially reduce oxidative stress in motor neurons and delay onset of amyotrophic lateral sclerosis (ALS) in ALS model mice (Morimoto et al., 2012).

Immunogen:

Native recombinant mouse TFAM protein with c-terminal 6-his tag

Protein Name(s):

TFAM (Transcription Factor A, motochondrial),

Gene Name(s):

TFAM

Antibody Registry ID:

Standard: AB_2492259
Trial Size: AB_2492259


Antibody Validation and Application Notes

Molecular Weight:

24 kDa