Anti-Synaptotagmin-10 Antibody (N269/73)

Name: Anti-Synaptotagmin-10 Antibody
Brand: NeuroMab
SKU: 75-262
Price: 295.0 USD
Availability: InStock

from NeuroMab Datasheet

Product Type

Primary Antibody

Species Reactivity

Mouse, Rat

Clone

N269/73

Applications

ICC, IHC, WB

Host Species

Mouse

Format

Purified

Gene Name

Syt10

Molecular Weight

60 kDa

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Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged Synaptotagmin plasmid and probed with N269/73 (left) and N86/8 (right) TC supe.

Volume: 100 µL

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Product Details

Target

Synaptotagmin-10 (Synaptotagmin X) (SytX)

Target Description

Synaptotagmins are a family of calcium sensing, membrane trafficking proteins. 17 different synaptotagmins have been identified in mammals. Synaptotagmin 10 has been shown to function as the Ca2+-sensor that triggers IGF-1 exocytosis in olfactory bulb neurons (Cao P. et al., 2011).

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N269/73

Isotype

IgG1

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Syt10

Molecular Weight

60 kDa

Antigen

Fusion protein amino acids 248-335 (cytoplasmic C2A domain) of mouse Synaptotagmin-10 (also known as Syt10, Synaptotagmin X and SytX, accession number Q9R0N4); Rat: 100% identity (88/88 amino acids identical); Human: 95% identity (84/88 amino acids identical)Greater than 75% identity with Synaptotagmin-6, Synaptotagmin-9 and Synaptotagmin-3

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_10671950

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

Does not cross-react with Synaptotagmin-6 or Synaptotagmin-3

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Synaptotagmin-10 (Synaptotagmin X) (SytX)

UniProt Details

UniProt (Human): Q6XYQ8
UniProt (Immunogen Species): Q9R0N4

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Anti-Synaptotagmin-10 Antibody (N269/73)

Anti-Synaptotagmin-10 Antibody
SKU: 75-262

Bulk Order Anti-Synaptotagmin-10 Antibody

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Anti-Synaptotagmin-10 Antibody (N269/73)

Anti-Synaptotagmin-10 Antibody SKU: 75-262

Bulk Order Anti-Synaptotagmin-10 Antibody

Product Details

Anti-Synaptotagmin-10 Antibody
SKU: 75-262