Anti-Neurexin-1-Beta (Blotting) Antibody (N170A/26)

Name: Anti-Neurexin-1-Beta (Blotting) Antibody
Brand: NeuroMab
SKU: 73-217
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

1 Citation

Product Type

Primary Antibody

Species Reactivity

Human, Mouse

Clone

N170A/26

Applications

ICC, WB

Host Species

Mouse

Format

TC Supernatant

Gene Name

NRXN1

Molecular Weight

50 kDa

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Transfected cell immunoblot: extracts of COS cells transiently transfected with Flag-tagged Neurexin-1-Alpha, Neurexin-1- Beta or untagged Kv2.1 plasmid and probed with N170A/26 TC supe (left) and rabbit anti-Flag (right).

Volume: 5 mL

Variant

Price:

$308

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Bulk Order Anti-Neurexin-1-Beta (Blotting) Antibody

Product Details

Target

Neurexin-1-beta (Neurexin I-beta)

Target Description

Neurexin-1Beta is a member of the neurexin family. Neurexin-1Beta is a membrane bound receptor and binds neuroligins and forms complexes at neuronal synapses in the central nervous system. Binding parterns for Neurexin 1beta include CASK, Neuroligins 1-3 and DAG1. Neurexin-1Beta serves as a presynaptic marker and plays an important role in assembling presynaptic and postsynaptic machinery. This protein may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins and possibly plays a role in synaptic junctions formation or maintenance.

Format

TC Supernatant

Concentration

Lot dependent

Clonality

Monoclonal

Clone

N170A/26

Isotype

IgG1

Applications

ICC, WB

Host Species

Mouse

Gene Name

NRXN1

Molecular Weight

50 kDa

Antigen

Synthetic peptide amino acids 47-64 (ASSLGAHHIHHFHGSSKH, extracellular N-terminus) of rat Neurexin-1-Beta (accession number Q63373) Human: 100% identity (18/18 amino acids identical); Greater than 60% identity with Neurexin-2-Beta

Species Reactivity

Human, Mouse

Antibody Registry ID

AB_10674585

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Conjugate

Unconjugated

Specificity

Does not cross-react with Neurexin-2-Beta

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Neurexin-1-beta (Neurexin I-beta)

UniProt Details

UniProt (Human): Q9ULB1
UniProt (Immunogen Species): P58400

Zeng L, Zhang P, Shi L, Yamamoto V, Lu W, Wang K. (2013), 'Functional impacts of NRXN1 knockdown on neurodevelopment in stem cell models..' PLoS One. 10.1371/journal.pone.0059685.

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Anti-Neurexin-1-Beta (Blotting) Antibody (N170A/26)

Anti-Neurexin-1-Beta (Blotting) Antibody
SKU: 73-217

Bulk Order Anti-Neurexin-1-Beta (Blotting) Antibody

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Anti-Neurexin-1-Beta (Blotting) Antibody (N170A/26)

Anti-Neurexin-1-Beta (Blotting) Antibody SKU: 73-217

Bulk Order Anti-Neurexin-1-Beta (Blotting) Antibody

Product Details

Anti-Neurexin-1-Beta (Blotting) Antibody
SKU: 73-217