Anti-MGL Antibody (N90/20)

Name: Anti-MGL Antibody
Brand: NeuroMab
SKU: 73-209
Price: 295.0 USD
Availability: InStock

from NeuroMab Datasheet

1 Citation

Product Type

Primary Antibody

Species Reactivity

Mouse, Rat

Clone

N90/20

Applications

ICC, WB

Host Species

Mouse

Format

TC Supernatant

Gene Name

Mgll Mgl2

Molecular Weight

35 kDa

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Volume: 5 mL

Variant

Price:

$295

Quantity:

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Product Details

Target

Monoglyceride lipase (MGL) (EC 3.1.1.23) (Monoacylglycerol lipase) (MAGL)

Target Description

Monoglyceride lipase, HU-K5 , MAGL or MGL is encoded by the gene MGL. MGL acts as a serine hydrolase of the AB hydrolase superfamily. This enzyme catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol and is involved in physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. (PubMed:19029917, PubMed:20079333, PubMed:21049984, PubMed:22969151, PubMed:24368842). MGL is found ubiquitously and highly expressed in adipose tissue, adrenal gland, ovary, heart, spleen, lung, skeletal muscle, kidney and brain. Diseases associated with this gene include Cannabis Dependence and Hallucinogen Dependence.

Format

TC Supernatant

Concentration

Lot dependent

Clonality

Monoclonal

Clone

N90/20

Isotype

IgG2b

Applications

ICC, WB

Host Species

Mouse

Gene Name

Mgll Mgl2

Molecular Weight

35 kDa

Antigen

Synthetic peptide amino acids 1-16 (MPEASSPRRTPQNVPY, N-terminus) of rat MGL (also known as Monoglyceride lipase, Mgll, Mgl2, HU-K5 and Lysophospholipase homolog, accession number Q8R431); Mouse: 100% identity (16/16 amino acids identical); Human: 81% identity (13/16 amino acids identical)

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2143198

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Conjugate

Unconjugated

Specificity

None Reported

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Monoglyceride lipase (MGL) (EC 3.1.1.23) (Monoacylglycerol lipase) (MAGL)

UniProt Details

UniProt (Human): Q99685
UniProt (Immunogen Species): Q8R431

Iannotti FA, Silvestri C, Mazzarella E, Martella A, Calvigioni D, Piscitelli F, Ambrosino P, Petrosino S, Czifra G, Bíró T, Harkany T, Taglialatela M, Di Marzo V. (2014), 'The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels..' Proceedings of the National Academy of Science of the United States of America. 10.1073/pnas.1406728111.

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Anti-MGL Antibody (N90/20)

Anti-MGL Antibody
SKU: 73-209

Bulk Order Anti-MGL Antibody

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Anti-MGL Antibody (N90/20)

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Anti-MGL Antibody
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