Monoglyceride lipase, HU-K5 , MAGL or MGL is encoded by the gene MGL. MGL acts as a serine hydrolase of the AB hydrolase superfamily. This enzyme catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol and is involved in physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. (PubMed:19029917, PubMed:20079333, PubMed:21049984, PubMed:22969151, PubMed:24368842). MGL is found ubiquitously and highly expressed in adipose tissue, adrenal gland, ovary, heart, spleen, lung, skeletal muscle, kidney and brain. Diseases associated with this gene include Cannabis Dependence and Hallucinogen Dependence.
TC Supernatant
Lot dependent
Monoclonal
N90/20
IgG2b
ICC, WB
Mouse
Mgll Mgl2
35 kDa
Synthetic peptide amino acids 1-16 (MPEASSPRRTPQNVPY, N-terminus) of rat MGL (also known as Monoglyceride lipase, Mgll, Mgl2, HU-K5 and Lysophospholipase homolog, accession number Q8R431); Mouse: 100% identity (16/16 amino acids identical); Human: 81% identity (13/16 amino acids identical)
Mouse, Rat
AB_2143198
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Unconjugated
None Reported
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
