Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3)
Potassium voltage-gated channel subfamily D member 3 or Kv4.3 potassium channel subunit is encoded by the gene KCND3. Kv4.3 is an alpha subunit of the voltage-gated potassium channel (Shal) family and mediates transmembrane potassium transport in excitable membranes. Kv4.3 is an integral membrane protein that combines to form tetramers. Kv4.3 is detected in the heart and brain. Diseases associated with this gene include Spinocerebellar Ataxia 19 and Brugada Syndrome.
TC Supernatant
Lot dependent
Monoclonal
K75/30
IgG2a
ICC, IHC, WB
Mouse
Kcnd3
70 kDa
Fusion protein amino acids 415-636 (cytoplasmic C- terminus) of rat Kv4.3 (also known as Potassium voltage-gated channel subfamily D member 3 and Kcnd3, accession number Q62897); Human: 99% identity (221/222 amino acids identical); Mouse: 99% identity (220/222 amino acids identical); >40% identity with Kv4.2 and Kv4.1 potassium channel subunits
Human, Mouse, Rat
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
DMEM, 10% FBS with supplements, 1X PenStrep, 10mM Sodium azide.
Unconjugated
Does not cross-react with Kv4.2
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
24 months from opening
Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3)
UniProt (Immunogen Species): Q62897
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