Homer protein homolog 1 (Homer-1) (VASP/Ena-related gene up-regulated during seizure and LTP 1) (Vesl-1)
Homer Scaffold Protein 1 is encoded by the gene HOMER1. Homer1 is a member of the Homer family of dendritic proteins. Homer1 is a postsynaptic density scaffolding protein which binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1, and SHANK3. HOMER1 is expressed in the skeletal muscle, heart, and brain. Diseases associated with HOMER1 include Phelan-Mcdermid Syndrome, bipolar disorder, autism, fragile x syndrome, and pervasive developmental disorder.
Purified
1 mg/mL
Monoclonal
L113/13
IgG1
AT, ICC, IHC, WB
Mouse
Homer1 Vesl1
50 kDa
Fusion protein amino acids 121-363 (C-terminus) of mouse Homer1 (also known as Homer protein homolog 1, VASP/Ena-related gene up-regulated during seizure and LTP 1, Vesl-1, Vesl, SYN47 and PSD-Zip45, accession number Q9Z2Y3); Rat: 97% identity (236/243 amino acids identical); Human: 93% identity (226/243 amino acids identical); 40% identity with Homer2
Human, Mouse, Rat
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Unconjugated
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
24 months from opening
Homer protein homolog 1 (Homer-1) (VASP/Ena-related gene up-regulated during seizure and LTP 1) (Vesl-1)
