Anti-GABA(A)R, Theta Antibody (L123/109)

Name: Anti-GABA(A)R, Theta Antibody
Brand: NeuroMab
SKU: 73-493
Price: 295.0 USD
Availability: InStock

from NeuroMab Datasheet

Product Type

Primary Antibody

Species Reactivity

Human

Clone

L123/109

Applications

ICC, IHC

Host Species

Mouse

Format

TC Supernatant

Gene Name

GABRQ

Molecular Weight

72 kDa

Go to Full Product Details

Adult human upper pons immunohistochemistry.

Volume: 5 mL

Variant

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$295

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Product Details

Target

GABA-A-R-Theta (Gamma-aminobutyric acid receptor subunit theta) (GABA(A) receptor subunit theta)

Target Description

Gamma-aminobutyric acid receptor subunit theta or GABA AR-Theta is encoded by the gene GABRQ. GABAA receptors are members of the Cys-loop family of ligand-gated ion channels. GABA AR theta is a subunit of the pentameric GABA receptors where GABA is the major inhibitory neurotransmitter in the vertebrate brain and mediates neuronal inhibition by binding to the GABA receptor and opening an integral chloride channel. GABA AR-theta is expressed in brain at the cell junction, synapse,and the postsynaptic cell membrane with high protein levels in the hypothalamus and dentate gyrus.

Format

TC Supernatant

Concentration

Lot dependent

Clonality

Monoclonal

Clone

L123/109

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

GABRQ

Molecular Weight

72 kDa

Antigen

Fusion protein amino acids 22-268 (extracellular N-terminus) of human GABA-A-R-Theta (also known as Gamma-aminobutyric acid receptor subunit theta, GABA(A) receptor subunit theta and GABRQ, accession number Q9UN88)

Species Reactivity

Human

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

DMEM, 10% FBS with supplements, 1X PenStrep, 10mM Sodium azide

Conjugate

Unconjugated

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Expiration

24 months from opening

Synonyms

GABA-A-R-Theta (Gamma-aminobutyric acid receptor subunit theta) (GABA(A) receptor subunit theta)

UniProt Details

UniProt (Human): Q86YM7
UniProt (Immunogen Species): Q9Z2Y3

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Anti-GABA(A)R, Theta Antibody (L123/109)

Anti-GABA(A)R, Theta Antibody
SKU: 73-493

Bulk Order Anti-GABA(A)R, Theta Antibody

Product Details

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Anti-GABA(A)R, Theta Antibody (L123/109)

Anti-GABA(A)R, Theta Antibody SKU: 73-493

Bulk Order Anti-GABA(A)R, Theta Antibody

Product Details

Anti-GABA(A)R, Theta Antibody
SKU: 73-493