Products: Primary Antibodies

Anti-Collagen 1, alpha 1 telopeptide Antibody

PhosphoSolutions Logo from PhosphoSolutions

 Datasheet

Product Summary:

Our rabbit polyclonal Collagen I, alpha 1, telopeptide antibody is affinity purified. It is excellent for use in WB and IHC.

PRODUCT OPTIONS

★ Trial Size Available ★
Brand Catalog # Option Volume Concentration Price
Brand
PhosphoSolutions Logo
Catalog #
322-COLT
Option
Standard
Volume
100 µL
Concentration
Lot dependent
Price
$380.00
Brand
PhosphoSolutions Logo
Catalog #
322-COLT-025
Option
Trial Size
Volume
25 µL
Concentration
Lot dependent
Price
$119.00

Validation Images


Product Details

Antibody Type:

Polyclonal

Host Species:

Rabbit

Form:

Antigen Affinity Purified

Species Reactivity:

Human Mouse Rat Sheep

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

IHC WB

Target Description:

Collagen is an extracellular matrix protein that serves as a scaffold defining the shape and mechanical properties of many tissues and organs including skin, tendon, artery walls, fibrocartilage, bone and teeth. Type 1 collagen is the most abundant protein in mammals. Collagens are synthesized with N-terminal and C-terminal propeptides that are cleaved during maturation and secretion. After cleavage of the propeptides, the most N-terminal and C-terminal remaining sequences are known as telopeptides. Mutations in the collagen 1, alpha 1 gene (COL1A1) are known to cause osteogenesis imperfecta (aka brittle bone disease) (Byers 1989). Furthermore, mutations found in the first 90 residues of the helical region of alpha 1 collagen have been implicated in the prevention or delayed removal of the procollagen N-propeptide leading to a combined osteogenesis imperfecta and Ehlers-Danlos syndrome (EDS) phenotype (Cabral et al., 2005).

Immunogen:

Synthetic peptide corresponding to amino acid residues specific to the collagen 1, alpha 1 telopeptide conjugated to KLH

Protein Name(s):

Collagen 1, alpha 1 telopeptide

Gene Name(s):

COL1A1

Antibody Registry ID:

Standard: AB_2492061
Trial Size: AB_2492061


Antibody Validation and Application Notes

Molecular Weight:

140 kDa