Products: Primary Antibodies

Anti-ChAT (Choline Acetyltransferase) Antibody

PhosphoSolutions Logo from PhosphoSolutions

 Datasheet

Product Summary:

Our goat polyclonal Choline Acetyltransferase total protein antibody is affinity purified. It is excellent for use in WB and IHC.

PRODUCT OPTIONS

★ Trial Size Available ★
Brand Catalog # Option Volume Concentration Price
Brand
PhosphoSolutions Logo
Catalog #
315-CHAT
Option
Standard
Volume
100 µL
Concentration
Lot dependent
Price
$380.00
Brand
PhosphoSolutions Logo
Catalog #
315-CHAT-025
Option
Trial Size
Volume
25 µL
Concentration
Lot dependent
Price
$119.00

Validation Images


Product Details

Antibody Type:

Polyclonal

Host Species:

Goat

Form:

Affinity Purified

Species Reactivity:

Chicken Guinea Pig Human Monkey Mouse Rat

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

IHC WB

Target Description:

Choline acetyltransferase is a neuronal enzyme which catalyzes the reaction between Acetyl CoA and choline resulting in the formation of acetylcholine. It is therefore found primarily in cholinergic neurons making it a valuable marker for diseases associated with decreased cholinergic function such as Schizophrenia, Alzheimer's disease (AD) and Down syndrome (Holt et al. 1999). Decreased choline acetyltransferase activity in particular has been shown in Schizophrenic subjects (Karson et al 1993). It has furthermore been demonstrated that in patients with AD, there are significantly lower levels of cortical ChAT that correlate with severity of the disease as measured by loss of neuropsychological function (Baskin et al. 1999).

Immunogen:

Recombinant human choline acetyltransferase

Protein Name(s):

ChAT (Choline Acetyltransferase), 315

Gene Name(s):

CHAT

Antibody Registry ID:

Standard: AB_2492055
Trial Size: AB_2492055


Antibody Validation and Application Notes

Molecular Weight:

70 kDa