Products: Primary Antibodies
Anti-ChAT (Choline Acetyltransferase) Antibody
from PhosphoSolutions
Our goat polyclonal Choline Acetyltransferase total protein antibody is affinity purified. It is excellent for use in WB and IHC.
PRODUCT OPTIONS
★ Trial Size Available ★| Brand | Catalog # | Option | Volume | Concentration | Price | |
|---|---|---|---|---|---|---|
| Brand |
Catalog # 315-CHAT |
Option Standard |
Volume 100 µL |
Concentration Lot dependent |
Price $390.00 |
|
| Brand |
Catalog # 315-CHAT-025 |
Option Trial Size |
Volume 25 µL |
Concentration Lot dependent |
Price $125.00 |
Validation Images
Product Details
Polyclonal
Goat
Affinity Purified
Chicken Guinea Pig Human Monkey Mouse Rat
IHC WB
Choline acetyltransferase is a neuronal enzyme which catalyzes the reaction between Acetyl CoA and choline resulting in the formation of acetylcholine. It is therefore found primarily in cholinergic neurons making it a valuable marker for diseases associated with decreased cholinergic function such as Schizophrenia, Alzheimer's disease (AD) and Down syndrome (Holt et al. 1999). Decreased choline acetyltransferase activity in particular has been shown in Schizophrenic subjects (Karson et al 1993). It has furthermore been demonstrated that in patients with AD, there are significantly lower levels of cortical ChAT that correlate with severity of the disease as measured by loss of neuropsychological function (Baskin et al. 1999).
Recombinant human choline acetyltransferase
ChAT (Choline Acetyltransferase), 315
CHAT
Standard: AB_2492055
Trial Size: AB_2492055
Antibody Validation and Application Notes
70 kDa