Anti-Cavß3 Calcium Channel Antibody (N473/36)

Name: Anti-Cavß3 Calcium Channel Antibody
Brand: NeuroMab
SKU: 75-472
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

N473/36

Applications

ICC, WB

Host Species

Mouse

Format

Purified

Gene Name

CACNB3 CACNLB3

Molecular Weight

60 kDa

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Immunoblot against extracts of COS cells transiently transfected with Myc¬Flag-tagged Cavbeta1, Cavbeta2, Cavbeta3, Cavbeta4 or untagged Kv2.1 plasmid probed with N473/86 (left) or mouse anti-Flag (right)..

Volume: 100 µL

Variant

Price:

$308

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Product Details

Target

Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3)

Target Description

Voltage-dependent L-type calcium channel subunit beta-3 or Cav ß3 is encoded by the gene CACNB3. Cavß3 is a cytoplasmic subunit of voltage-sensitive calcium channels.These channels facilitate entry of calcium ions into excitable cells are involved in a variety of calcium dependent processes, including neurotransmitter release, muscle contraction, and gene expression. Cav ß3 is expressed in brain, colon and ovary. Diseases associated with this gene include Lambert-Eaton Myasthenic Syndrome.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N473/36

Isotype

IgG2b

Applications

ICC, WB

Host Species

Mouse

Gene Name

CACNB3 CACNLB3

Molecular Weight

60 kDa

Antigen

Fusion protein amino acids 20-149 (N-terminus) of human Cavbeta3 (also known as Voltagedependent L-type calcium channel subunit beta-3, Calcium channel voltage-dependent subunit beta 3, CAB3, CACNB3, CACNLB3 and CCHB3, accession number P54284); Rat: 100% identity (130/130 amino acids identical); Mouse: 99% identity (129/130 amino acids identical); 70% identity with Cavbeta4 and other calcium channel subunits

Species Reactivity

Human, Mouse, Rat

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

Does not cross-react with Cavbeta1, Cavbeta2 or Cavbeta4

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3)

UniProt Details

UniProt (Human): P54284
UniProt (Immunogen Species): P54284

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Anti-Cavß3 Calcium Channel Antibody (N473/36)

Anti-Cavß3 Calcium Channel Antibody
SKU: 75-472

Bulk Order Anti-Cavß3 Calcium Channel Antibody

Product Details

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Anti-Cavß3 Calcium Channel Antibody (N473/36)

Anti-Cavß3 Calcium Channel Antibody SKU: 75-472

Bulk Order Anti-Cavß3 Calcium Channel Antibody

Product Details

Anti-Cavß3 Calcium Channel Antibody
SKU: 75-472