Immunology News & Publications Regarding Antibodies Incorporated

We are developing serological and direct detection ELISA-based tests for Blastocystis. Distinguishing the antibody response to specific subtypes may provide insights into pathology.

Blastocystis is a gastrointestinal parasite causing symptoms often associated with irritable bowel syndrome. The prevalence of this organism seems to be rising as more and more veterans of our Middle East wars are being found positive for Blastocystis. Clinical diagnosis of this organism currently depends on microscopic analysis of fecal samples, although PCR tests are available and may be useful in diagnosis. Some of the subtypes of the organism may be uniquely associated with antibody responses in patients and perhaps with pathogenicity, as well, but there is much disagreement in the literature.

Chinese Journal of Pharmacology and Toxicology (1995) May; 9(2) 146-148

Micronuclei, CREST-positive micronuclei and cell inactivation induced in Chinese hamster cells by radiation with different quality.

Mutation Research 343 (1995) 85-94 Genotoxicity of quercetin in the micronucleus assay in mouse bone marrow erythrocytes, human lymphocytes, V79 cell line and identification of kinetochore-containing (CREST staining) micronuclei in human lymphocytes

Authors: Helena Caria, Teresa Chaveca, Antonia Laires, Jose Rueff

This article is not posted on the web. Please contact Mutation Research to request the article from the Genetic Toxicology journal. www.mutationresearch.com