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Your protein or molecule can be used to create hybridomas that produce monoclonal antibodies. We have been producing hybridomas and monoclonal antibodies since 1976. Monoclonal antibodies have certain advantages over polyclonal antibodies:
• Reproducibility over long term of use.
• Specificity to only single epitopes.
• Can be engineered into therapeutic antibodies.
Our scientists will be happy to discuss your design input requirements.
Important aspects of design input include:
• Type and specifi city of antibody required.
• Nature of the antigen
- Proper display of desired epitopes.
- Immunogenicity.
• Assay design
- The assay should be quick and easy to perform on several hundred
potential cultures.
- ELISA assays are classically used, though Western Blot, Flow Cytometry,
Immunoprecipitation are possible.
- Existing positive controls are very helpful.
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